NPM package vulnerabilities

Hello

We were reviewing the npm packages and we are intersted in updating some packages including karma. However there is a warning that there could be some breaking changes, we are curious to know what sort of breaking changes these could be and how hard it would be to fix them. We would like to update to version 6.4.4 and we see that the package is currently at version 0.13.22. Has anyone done this sort of work before? Any help would be appreciated.